A Message from Dr Engel

Dear Colleagues,

HLDA9 / Barcelona

The 9th International Conference on Human Leukocyte Differentiation Antigens (HLDA9) was held at the Fundació Academia de Ciencies Mèdiques i de la Salut de Catalunya i de Balears in Barcelona, 11-13 March 2010. In attendance were more than 200 scientists and clinicians from 18 different countries, including persons from Canada, China, the Czech Republic, England, France, Germany, Hungary, Israel, Italy Japan, Mexico, Norway, Poland, Russia, Slovakia, Spain, Sweden, the Ukraine, and the United States.

I would like to express my sincere thanks to all of you who attended and contributed to HLDA9. I was extremely pleased with the high quality of the work shown at all levels – from posters to special session oral presentations to plenary talks. It was also encouraging to see so many of you at the Gala Dinner.

More importantly, as someone who has attended nearly all of the HLDA Conferences, it was rewarding to see so many young scientists, from many different nations, participating and building upon the work begun nearly 30 years ago.

 

Validation files for the new CDs and other submitted antibodies

For those of you who are interested, validation files for the new CDs, as well as other submitted mAbs (including those against intracellular molecules) will be posted during the forthcoming months at the HLDA Workshop webpage (www.hlda9.org).

We hope to greatly expand and enhance this site over the next year to make it a very worthwhile destination not only for those working in this field, but also for researchers in other disciplines.

 

Validating new CDs

As Dr. Boumsell mentioned in her closing plenary talk "Perspective on Future Developments", HCDM-HLDA plans to make the submission of antibodies readily available to researchers year-round, and not just at the international workshops/conferences held every 3 to 5 years.

More information will be forthcoming on this once a submission procedure has been established.

---------------------------------

 

For all of these future developments, we encourage you to bookmark and visit the HLDA Workshop page (www.hlda9.org).

Again, thank you all for participating and contributing to HLDA9. It is you who have made it such a success. I look forward to interacting and working with you again in the near future.

All the best,

 

Pablo Engel, M.D., Ph.D. (Chair, HLDA9)

 

Intracellular Antigens

This table lists the antibodies to intracellular antigens which were submitted to the HLDA9 Workshop and were validated as specific to a Cluster of Differentiation (CD).

Files containing the validation data can be accessed by clicking on the Workshop Number (opens a pdf file).

Workshop Number
Specificity
Clone name
mAb Species
Isotype
Submitter
GCET-1
RAM-341B
Mouse
IgG1
CNIO
XBP-1s
143F
Mouse
IgG2a
CNIO
BLK
BLK154
Mouse
IgG1
University of Oxford
BCL11A-XL
BCL123a
Mouse
IgG2
University of Oxford
FOXP1
JC12
Mouse
IgG2a
University of Oxford/USD
LSP1
TPD153
Mouse
IgG2
University of Oxford
FOXP3
236A/E7
Mouse
IgG2
CNIO
BCL6
GI191E
Mouse
IgG1
CNIO
BCL2
NOR 235
Rat
IgG2
CNIO
FOXP2
FOXP2-73A/8
Mouse
IgG1
University of Oxford

Cell Surface Molecules

Workshop Number
Specificity
Clone name
mAb Species
Isotype
Submitter
CD352
292811
Mouse
IgG2a
RandD Systems
CD307b
296902
Mouse
IgG1
RandD Systems
CD307a
E3
Mouse
IgG1
Sanford Research/USD
CD307b
B24
Mouse
IgG2a
Sanford Research/USD
CD307c
H5
Mouse
IgG2b
Sanford Research/USD
CD307d
A1
Mouse
IgG2a
Sanford Research/USD
CD210a
3F9
Rat
IgG2ak
BD Biosciences
CD329
E10-286
Mouse
IgG1k
BD Biosciences
CD80
L307.4
Mouse
IgG1k
BD Biosciences
CD261
DJR1
Mouse
IgG1k
eBioscience
CD262
DJR2-4
Mouse
IgG1k
eBioscience
CD354
193015
Mouse
IgG1
RandD Systems
CD329
191240
Mouse
IgG2a
RandD Systems
CD355
210213
Mouse
IgG2b
RandD Systems
CD357
621
Mouse
IgG1k
BioLegend
TNFRSF6B
B08-35
Mouse
IgG1k
RandD Systems
CD352
NT-7
Mouse
IgG1k
BioLegend
CD270
122
Mouse
IgG1k
BioLegend
Galectin-3
Gal397
Mouse
IgG1k
BioLegend
CD354
TREM-26
Mouse
IgG1k
BioLegend
CD307a
E9
Mouse
IgG1k
Sanford Research/USD
CD363
218713
Mouse
IgG2b
RandD Systems
CD22
CTSU-CD22-1
Mouse
IgG1
Southampton General Hospital
CD22
CTSU-CD22-2
Mouse
IgG1
Southampton General Hospital
CD22
CTSU-CD22-5
Mouse
IgG1
Southampton General Hospital
CD22
CTSU-CD22-6
Mouse
IgG1
Southampton General Hospital
CD22
CTSU-CD22-8
Mouse
IgG1
Southampton General Hospital
CD38
1D20C1
Mouse
IgG
University of Verona
CD38
1E82G1
Mouse
IgG
University of Verona
CD38
1F82E1
Mouse
IgG
University of Verona
CD38
2C22B10
Mouse
IgG
University of Verona
CD38
1E80D1
Mouse
IgG
University of Verona
CD38
1E82H11
Mouse
IgG
University of Verona
CD38
2A40C2
Mouse
IgG
University of Verona
CD38
2D42E1
Mouse
IgG
University of Verona
CD40
4H8
Human
IgM
IMIM
CD5
8B10d
Human
IgM
IMIM
CD215
JM7A4
Mouse
IgG2bk
BioLegend
CD362
305515
Rat
IgG2b
RandD Systems
CD360
152512
Mouse
IgG1
RandD Systems
CD253
2E5
Mouse
IgG2
ExBio
CD358
DR-6-04-EC
Mouse
IgG1
ExBio
CD262
DR5-01-1
Mouse
IgG1
ExBio
CD263
TRAIL-R3-02
Mouse
IgG1
ExBio
CD261
DR-4-02
Mouse
IgG1
ExBio
CD80
MEM-233
Mouse
IgG1
ExBio
CD262
DR5-01-4
Mouse
IgG1
ExBio
CD264
TRAIL-R4-01
Mouse
IgG1
ExBio
CD361
MEM-216
Mouse
IgG1
Inst Of Molecular Genetics AS CR
CD3
1774-1; EP449E; EP29
Rabbit
IgG
EPITOMICS
CD20
1632-1; EP459Y; EP7
Rabbit
IgG
EPITOMICS
CD79a/mb1
2613-1; EP3618; EP27
Rabbit
IgG
EPITOMICS
CD351
TX61
Mouse
IgG1
University of Tsukuba
CD353
SF8.748
Mouse
IgG1
University of Barcelona

New CD Molecules

CD Number Gene Name Full Name (NCBI) Alternate Names Gene Family
CD210 IL10RA interleukin 10 receptor, alpha IL10R; CDW210A; HIL-10R; IL-10R1; IL10RA Type II Cytokine Receptor
CD215 IL15RA interleukin 15 receptor, alpha IL15RA Type I Cytokine Receptor
CD270 TNFRSF14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) TR2; ATAR; HVEA; HVEM; LIGHTR; TNFRSF14 TNF Receptor SF
CD307a FCRL1 Fc receptor-like 1 FCRH1; IFGP1; IRTA5; FCRL1 Immunoglobulin SF (FcR-Like Family)
CD307b FCRL2 Fc receptor-like 2 FCRH2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C; FCRL2 Immunoglobulin SF (FcR-Like Family)
CD307c FCRL3 Fc receptor-like 3 FCRH3; IFGP3; IRTA3; SPAP2; FCRL3 Immunoglobulin SF (FcR-Like Family)
CD307d FCRL4 Fc receptor-like 4 FCRH4; IGFP2; IRTA1; FCRL4 Immunoglobulin SF (FcR-Like Family)
CD307e FCRL5 Fc receptor-like 5 CD307; FCRH5; IRTA2; BXMAS1; PRO820 Immunoglobulin SF (FcR-Like Family)
CD351 FCAMR Fc receptor, IgA, IgM, high affinity FCA/MR; FKSG87; FCAMR Immunoglobulin SF (Fc-Receptor Family)
CD352 SLAMF6 SLAM family member 6 KALI; NTBA; KALIb; Ly108; NTB-A; SF2000 Immunoglobulin SF (SLAM Family)
CD353 SLAMF8 SLAM family member 8 BLAME; SBBI42 Immunoglobulin SF (SLAM Family)
CD354 TREM1 triggering receptor expressed on myeloid cells 1 TREM-1 Immunoglobulin SF
CD355 CRTAM cytotoxic and regulatory T cell molecule CRTAM Immunoglobulin SF
CD357 TNFRSF18 tumor necrosis factor receptor superfamily, member 18 AITR; GITR; GITR-D; TNFRSF18 TNF Receptor SF
CD358 TNFRSF21 tumor necrosis factor receptor superfamily, member 21 DR6; BM-018; TNFRSF21 TNF Receptor SF
CD360 IL21R interleukin 21 receptor NILR Type I Cytokine Receptor
CD361 EVI2B ecotropic viral integration site 2B EVDB; D17S376; EVI2B  
CD362 SDC2 syndecan 2 HSPG; HSPG1; SYND2; SDC2 syndecan proteoglycan family
CD363 S1PR1 sphingosine-1-phosphate receptor 1 EDG1; S1P1; ECGF1; EDG-1; CHEDG1 GPCR
CD364 PI16 peptidase inhibitor 16 dJ90K10.5; MGC45378; MSMBBP  

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